TGEN APPLICATION.PDF

SALT RIVER PIMA-MARICOPA
INDIAN COMMUNITY
10,005 E. Osborn Road, Scottsdale, Arizona 85256 / Phone 480-362-7520 / Fax 480-362-7593
12% Gaming Contributions Application
Date of Application: June 14, 2013
Organization Name: Translational Genomics Research Institute (TGen)
OrganizationAVIunicipal Government Street & Mailing Address: Maricopa County, Government
Relations, 301 W. Jefferson, 10 th Floor, Phoenix, Arizona 85255
Contact Person and Project Manager if different from Contact Person: Kristen Elnicky
Title: Director of Foundation Operations
Address: 445 N. 5t1 Suite 120, Phoenix, AZ 85004
Phone: (602) 343-8432
Fax: (602) 343-8441
Email Address: kelnicky@tgen.org
Project Name: Molecular Profiling of Diseases and Disorders
In 200 words or less, please provide a brief description of the project submitted to the
12% SRPMIC Grant program.
Thanks to the prior generous support of the Salt River Pima-Maricopa Indian Community to help fund
TGen's Next Generation Sequencing capabilities and other genomic research technologies, TGen is now
able to examine the molecular mechanism underpinning the basis of rare and devastating diseases and
disorders in a way that has never before been possible.
TGen is committed to developing, refining, and applying the latest tools of genomic medicine to the
diagnosis and treatment of patients. We use the most advanced technology and analytical approaches to
identify specific changes in a person's DNA. By understanding how those changes lead to disease, we can
begin the search for treatments and therapies tailored to each patient. Additionally, our methods allow us
to reach beyond the sequencing of a genome to include the measurement of other biomolecules, such as
proteins. Our laboratories then work side-by-side with the patients' doctors to search for treatment options
that work.
Until now, many diseases have gone undiagnosed or misdiagnosed for years, leaving patients and their
families to suffer needlessly. In conjunction with our clinical partners, TGen now has the ability to
accurately diagnose such diseases and disorders, bringing hope to patients throughout Arizona and around
the world.
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Beginning Date of Project: Ongoing Research End Date of Project: Ongoing Research
Geographic Area to be served: Maricopa County, as well as the State of Arizona
** Attach Detailed Budget**
Amount of Total Project: Scalable Project Amount of 12% Request: $150,000
(No Multi-Year Request will be accepted)
If the Amount of funding received is less than the amount needed for the project, do you have other
funds to complete the project? (Please Explain):
TGen will continue to rely on funding from grants, contracts, and additional philanthropic gifts.
If you receive SRPMIC 12 % funding, will it be spent (Check One):
X Monthly
El Quarterly
II Lump Sum
List of SRPMIC 12% funds you have received in the past and a list of other 12 % grants funding
you are seeking from other Tribal Governments for the 2012-2013 12% cycle.
Year Amo un 1 Purpose
Jun-03 $5 million pledge Diabetes research
Oct-03 $1 million payment Diabetes research
Nov-04 $1 million payment Diabetes research
Dec-05 $1 million payment Diabetes research
Nov-04 $2 million payment Diabetes research
Jan-10 $200,000 Key technologies
Dec-10 $175,000 Next generation sequencing
Dec-11 $175,000 Next generation sequencing
Jan-13 $150,000 Next generation sequencing
TGen has also requested $50,000 from the Tohono 0' odham Nation for the 2012-2013 12% cycle.
List any other funds you have received from the SRP1VHC and identify the source:
N/A
Funding for project/programs may be based on available funding. As such, if funding were not
available for the full the amount of request how would you prioritize funding.
The program is scalable, and the funding would be used to sequence the genomes of as many patients as
possible.
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Which municipal governmental entity will serve as your pass through or accept 12% funds on your
behalf?
Maricopa County
By execution of the 12% Gaming Contribution Grant Application the undersigned agrees that the
information contained in the Application is true to the best of the Applicants knowledge. The
Applicant shall notify the SRPMIC if any information in this Application changes.
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Name and Title
The Application shall be signed by the senior elected official of the local government, or in the case
of a non-profit entity, the Chief Executive Officer authorizes to commit the non-profit entity to
apply for, accept, and implement an award from the SRPMIC utilizing 12% Gaming
Contributions.
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...0„ai MAWS RESEARCH HUME Budget
Project Name: Molecular Profiling of Diseases and Disorders
Amount
Sequencing Costs $ 100,000
Data Administration $ 20,000
IT and Technology Support $ 20,000
Project Management $ 10,000
Total: $ 150,000
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